Supplementary Figure 1: Overview of other approaches. | Nature Methods

Supplementary Figure 1: Overview of other approaches.

From: Interpretation of an individual functional genomics experiment guided by massive public data

Supplementary Figure 1

(left) Coexpression networks are based entirely on the correlated expression in a specific dataset. This yields functional relationships that are highly relevant to the specific dataset but does not capture accurately biological pathway interactions. (right) A generic Bayesian integration using a global data compendium accurately identifies biological pathway interactions, but the functional relationships in this network have a low specificity to any specific dataset.

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