Supplementary Figure 1: 3D classification of the CNG dataset.
From: A particle-filter framework for robust cryo-EM 3D reconstruction
a-d) are four classes calculated from 211,826 particles after one round of filtering by 2D classification in our previous work17. The side view (left) and top view (right) are shown. The model with C4 symmetry (PDB entry code: 5h3o) was docked in the maps. The uncovered models, pointed to by orange arrows, indicate the missing part of the subunit in the trans-membrane region of the CNG channel.
