Supplementary Figure 10: Simultaneous activation of endogenous genes by catalytically active AsCas12a-VPR and crRNA arrays. | Nature Methods

Supplementary Figure 10: Simultaneous activation of endogenous genes by catalytically active AsCas12a-VPR and crRNA arrays.

From: Multiplexed orthogonal genome editing and transcriptional activation by Cas12a

Supplementary Figure 10

Relative mRNA expression after co-transfection of HEK293T cells with AsCas12a-VPR and crRNA arrays. Multiplex expression of 15-nt guides expressed from a single array versus respective single crRNAs targeting the promoter region of MIAT, or MYOD1. Mean ± s.d.; N = 3 independent experiments.

Back to article page