Supplementary Figure 4: Trogocytosis occurs among various TCR and pMHC allele pairs. | Nature Methods

Supplementary Figure 4: Trogocytosis occurs among various TCR and pMHC allele pairs.

From: T cell antigen discovery via trogocytosis

Supplementary Figure 4

(a) Antigen-specific trogocytosis between Jurkat expressing B07-, B18- or C03-restricted NY-ESO-1-specific TCRs and K562 expressing their cognate antigens (10:1 J:K). (b) Comparison of trogocytosis capability 1G4-Jurkat cells or Jurkat cell expressing four other novel A2-restricted NYESO-specific TCRs with NYESO1-K562 cells (10:1 J:K). (c) Comparison of trogocytosis capability F5-Jurkat cells or Jurkat cell expressing low-affinity M1W-TCR with MART1-K562 cells (5:1 J:K). Data are presented as mean ± s.e.m. and are representative of two independent experiments.

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