Supplementary Figure 7: Binary FDR-based crRNA array enrichment analyses.
From: In vivo profiling of metastatic double knockouts through CRISPR–Cpf1 screens
a, Venn diagram of gene pairs that were enriched in ≥50% of primary tumors or lung metastases. b,c, Histogram detailing the percentage of independent crRNA arrays that were enriched in primary tumors (b) or lung metastases (c) for each single gene (left) or gene pair (middle). Right, table of the top genes/gene pairs in terms of the percentage of independent crRNA arrays that were enriched in primary tumors (b) or lung metastases (c). Text colors correspond to the histograms. d–f, Enrichment bar plots of multiple independent crRNA arrays targeting Nf2_Rb1 (d), Nf2_Pten (e) and Nf2_Trim72 (f) in lung metastases (n = 37 from ten mice).
