Supplementary Figure 9: Additional analyses of synergistic metastasis drivers.
From: In vivo profiling of metastatic double knockouts through CRISPR–Cpf1 screens
a–e, Tukey box plots (IQR boxes with 1.5 × IQR whiskers and notched 95% confidence interval of median) detailing the log2 RPM abundances of the indicated genotypes in lung metastases (n = 37 from ten mice), with associated two-sided Wilcoxon rank sum P values and SynCo scores noted. a, Chd1_Kmt2d. b, Chd1_Nf2. c, Jak1_Kmt2c. d, Nf1_Pten. e, Kmt2d_Pten. Statistics are in reference to the DKO genotype (purple) and colored according to the corresponding SKO genotype (green and orange).
