Supplementary Figure 8: Characteristics of clusters from TT-RNA profiles.
From: Integrated transcriptomic–genomic tool Texomer profiles cancer tissues
a, Most clusters express cluster-specific KEGG pathways based on GSEA (P < 0.01, n = 570 genes). b,c, The association between clusters from TT-RNA profile and PAM50 subtype (b) and the association between clusters from bulk RNA profile and PAM50 subtypes (c). Log(ratio) in y-axis represent log2 transformation of the subtype enrichment ratios. Dashed line corresponds to ratio = 1.5. d–f, Progression free survival (PFS) analysis based on eight Texomer-derived clusters, PAM50 subtypes and four clusters derived from bulk RNA profile, respectively. P value determined by two-sided log-rank test.
