Supplementary Figure 10: Variance component analysis of RNA profile explained by DNA profile.
From: Integrated transcriptomic–genomic tool Texomer profiles cancer tissues
a,b, The variance of the bulk WTS read counts explained by the bulk WES read counts (Bulk RNA: Bulk DNA), variance of the bulk WTS read counts explained by the TT-DNA copy-number profile (Bulk RNA: TT-DNA), and variance of the TT-RNA expression profile explained by the TT-DNA copy-number profile (TT-RNA: TT-DNA) derived from the total and the allele-specific level using breast cancer cell line HCC1143 (a) and in silico simulation data (b). ‘Expected’ represented the proportion of variance estimated from the isogenic tumor cell line (HCC1143) data or specified in simulation.
