Supplementary Figure 1: The best signal-to-noise ratio (SNR) of in vivo dendritic spine morphological and calcium imaging in previously published work.
From: Direct wavefront sensing enables functional imaging of infragranular axons and spines
(a, b) Comparison of in vivo dendritic spine morphological imaging SNR among previous works using traditional two-photon microscopy or with adaptive optics at different depth. Subgraph in the bottom left corner of a shows how to estimate SNR. The images for SNR estimation are directly imported from the publications. The arrows in panel a indicate the increase of the SNR by adaptive optics. (c) Comparison of in vivo dendritic spine calcium functional imaging SNR among previous works using traditional two-photon microscopy or with adaptive optics at different depth. Subgraph in the bottom left corner shows how to estimate the SNR of dendritic spine calcium signal.
