Supplementary Figure 14: DART-Seq does not identify m6Am sites. | Nature Methods

Supplementary Figure 14: DART-Seq does not identify m6Am sites.

From: DART-seq: an antibody-free method for global m6A detection

Supplementary Figure 14

Regions surrounding DART-Seq sites overlap with a single predicted m6Am site in CDC42BPA. However, DART-Seq reads showing at least 10% C to U conversion (gold to green, respectively) indicate reduction of C to U editing in METTL3-depleted (METTL3 KD) cells, suggesting that this is an m6A and not an m6Am site. The putative m6A/m6Am site (yellow) is also located in a DRACH motif and internally within the 5’UTR. Percentages indicate proportion of C to U editing event at that site.

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