Supplementary Figure 5: Estimated mutational signature exposures based upon the tri-nucleotide context of somatic SNVs called from whole-exome sequencing (WES) data for n=32 HipSci human fibroblast lines. | Nature Methods

Supplementary Figure 5: Estimated mutational signature exposures based upon the tri-nucleotide context of somatic SNVs called from whole-exome sequencing (WES) data for n=32 HipSci human fibroblast lines.

From: Cardelino: computational integration of somatic clonal substructure and single-cell transcriptomes

Supplementary Figure 5

The x-axis shows 30 COSMIC mutational signatures, in order, and the y-axis shows estimated exposures (mutation fraction) using the sigfit package (Methods), with significant signatures highlighted in blue. Across lines, the only significant signatures are Signature 7 (UV mutagenic process) and Signature 11.

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