Extended Data Fig. 9: The comparation of BE3-FNLS, YE1-BE3-FNLS and BE4max. | Nature Methods

Extended Data Fig. 9: The comparation of BE3-FNLS, YE1-BE3-FNLS and BE4max.

From: A rationally engineered cytosine base editor retains high on-target activity while reducing both DNA and RNA off-target effects

Extended Data Fig. 9

a, The C-to-T editing efficiency for BE3-FNLS, YE1-BE3-FNLS and BE4max at indicated target sites. b, Indel frequency for BE3-FNLS, YE1-BE3-FNLS and BE4max at indicated target sites. Data are shown as mean values ± SEM for n = 3 biological replicates performed at the same time. P value was calculated by two-sided Student’s t-test.

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