Extended Data Fig. 3: Analysis of the L1000 panel.
From: Targeted Perturb-seq enables genome-scale genetic screens in single cells
a, Spearman correlation in mean gene expression levels between TAP-seq and whole transcriptome readout (Whole Tx) for a panel targeting the L1000 gene set34. n = 6,963 genes were covered in TAP-seq and are included in the plot. b, Principal component analysis of the TAP-seq dataset and the whole transcriptome dataset. Principal component loadings of all genes annotated in cyclebase v351 are shown, with the peak-time of expression color-coded. In the whole transcriptome dataset, PC1-3 were not significantly associated with GO-terms (not shown). n = 68,734 cells (TAP-seq) and 8,282 cells (Whole Tx).
