Extended Data Fig. 7: Reconstruction of complex SVs in 50 cancer samples. | Nature Methods

Extended Data Fig. 7: Reconstruction of complex SVs in 50 cancer samples.

From: Genome-wide detection of enhancer-hijacking events from chromatin interaction data in rearranged genomes

Extended Data Fig. 7

a, Number of assembled complex SVs in each sample. Only samples with complex SVs detected are shown. b, Size distributions of complex SV fragments, simple inversions and simple deletions/duplications. Data were merged from eight cancer cell lines: A549, Caki2, K562, LNCaP, NCI-H460, PANC-1, SK-N-MC, and T47D. For the boxplot, the box represents the interquartile range (IQR, Q3-Q1), the white dot represents the median, the upper whisker extends to the last datum less than Q3 + 1.5×IQR, and the lower whisker extends to the first datum greater than Q1-1.5×IQR. c, Percentage of transition between different SV types in a complex SV assembly, averaged from our analysis in 50 cancer cell lines/tissues.

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