Extended Data Fig. 10: Application of SnapHiC to identify loops in specific cell types.
From: SnapHiC: a computational pipeline to identify chromatin loops from single-cell Hi-C data
a, Top seven enriched gene ontology (GO) terms of genes associated with Astro-specific, MG-specific, ODC-specific and L2/3-specific SnapHiC loops. The p-values are calculated based on the accumulative hypergeometric distribution. b, Matrix of the percentage of cells with significantly higher normalized contact frequency (percentage of outlier cells with normalized contact frequency>1.96) for 261 astrocytes around APOE gene. The two SnapHiC-identified loops from astrocyte are marked by black squares and their labels matched the numbers shown in Fig. 2c.
