Extended Data Fig. 3: Quantitative compartment detection differ between protocols.
From: Systematic evaluation of chromosome conformation capture assays
a. Hierarchical clustering of Spearman correlations of Eigenvectors (PC1) for 63 protocols. Clustering shows strong correlations between compartments from data obtained with varying protocols applied to the same cell types and weaker correlations for data obtained with the same protocols applied to different cell types. b–e. A-A and B-B compartment strength of saddle plots for fixation versus enzyme stratified by cell state: DE (b), H1-hESC (c), HeLa-S3-NS (d), HFF (e). For each cell type, saddle plot quantification was done for cis and trans reads separately.
