Extended Data Fig. 6: Effect of lag time on calculated diffusion coefficients.
(a) Average median diffusion coefficient and (b) corresponding interquartile range vs chosen lag time (t) for each oligomeric species from n = 4 independent ΔPRD measurements (ntetramer = 213, ntetramer = 937, nhexamer = 330, ndecamer = 83; trajectories data shown in Supplementary Fig. 8-9). As the distribution of diffusion coefficients broadened significantly as the lag time increased, the diffusion coefficient of each oligomer was determined by taking the median of the distribution instead of Gaussian fitting. Each data point represents the mean diffusion coefficient from the median values determined from four repeats of ΔPRD measurements and the error bars are presented as mean values ± s.d..
