Extended Data Fig. 9: Results of simulated ground truth electrophysiology experiments.
From: Removing independent noise in systems neuroscience data using DeepInterpolation
(a) Right: Heatmap of original data (black outline), data with superimposed spike waveforms (gray outline), and superimposed data after denoising (red outline). Left: Spike waveform outlined in heatmaps, for three different conditions. (b) Mean peak waveforms for each of three units superimposed on the original data at 8 different amplitudes (N = 100 spikes per unit per amplitude). (c) Mean cosine similarity between individual denoised waveforms and the original superimposed waveform. Colors represent different units. (d) Relationship between denoised amplitude and waveform full-width at half max (FWHM), for all 100 µV waveforms. Colors represent different units.
