Extended Data Fig. 2: Signal to noise variation with lateral distance from center of rotation.

Graph showing the signal to noise variation with lateral off-set from centre of rotation. Pearson correlation coefficient (r) = -0.25 and p-value =0.21 (two-tailed test) shown on graph. It should be noted that the exposure time of the camera and final selection of the X-ray filters were set-up on the most off-centre scan, at the angle where the beam was crossing the smallest amount of material, in order to ensure that detector saturation would not occur during scanning. B) showing an example of the regions used to calculate the SNR. Signal was taken from tubule walls while the open tubule lumen was used as the background region.