Extended Data Fig. 10: Theoretical nanoantenna kinetic signatures for different types of inhibitors.

Here, we generated the expected spike profile of a theoretical system with the parameters: k_cat = 100 s⁻¹, K_M = 10 µM, [enzyme] = 100 nM, [substrate] = 1000 µM, and [inhibitor] = 125 µM. Shown are the effects of (a) competitive inhibitors with K_i = 100 µM and K_i = 1 µM, (b) uncompetitive inhibitor with K_i = 100 µM, and (c) non-competitive inhibitor with K_i = 100 µM.