Extended Data Fig. 2: Multi-scale 3D pathology of human prostate tissue.
From: A hybrid open-top light-sheet microscope for versatile multi-scale imaging of cleared tissues
(a) Fast meso-scale screening results for a multi-cm-sized piece of human prostate tissue stained with TO-PRO-3 Iodide (nuclear) and Eosin. Representative high-resolution regions of interests for two different foci of cancer are shown in (b) and (c). The insets demonstrate the ability to clearly resolve sub-nuclear features in cancer nuclei. Scale bar lengths are as follows: (a) 1 cm, (b) and (c) 10 μm. The imaging data in (a-c) was acquired from in a single experiment, which was not repeated.
