Fig. 5: Analysis of BNPs in conditioned cell culture medium containing serum.
a, Kymograph of multiple lipoprotein particles (red arrows) and one larger EV (blue arrow) moving through the nanochannel. Inset, schematics of an EV and a lipoprotein (depicted to scale). b,c, Scatter plots of iOC and D translated into RS. d,e, Histograms of RS, analyzed using ML. Data correspond to the conditioned SH-SY5Y human cell medium (b,d) and to the control where the medium had not been in contact with the cells (c,e). All data were acquired in Channel V, which had been passivated by an SLB before measurement.
