Extended Data Fig. 4: Machine-learning analysis results. | Nature Methods

Extended Data Fig. 4: Machine-learning analysis results.

From: Label-free nanofluidic scattering microscopy of size and mass of single diffusing molecules and nanoparticles

Extended Data Fig. 4

(A, B) Scatter plots of iOC translated into MW using Eq. 1 in the main text, and D translated into RS using Eq. 2 in the main text for individual biomolecules of different types, measured in (A) Channel I and (B) Channel II using ML. Each dot is extracted from a single biomolecule trajectory. Color intensity scales linearly with frame number of the trajectory (N). The highest intensity corresponds to N = 2130 frames. The gray line corresponds to an empirical relation between MW and D for globular protein30 (C, D) iOC histograms of the biomolecules in (A, B) translated into MW using Eq. 1 in the main text.

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