Extended Data Fig. 8: Generation of CD4 + and CD8 + T cells in hu.Thor mice. | Nature Methods

Extended Data Fig. 8: Generation of CD4 + and CD8 + T cells in hu.Thor mice.

From: De novo construction of T cell compartment in humanized mice engrafted with iPSC-derived thymus organoids

Extended Data Fig. 8

Splenocytes were harvested from hu.SRC (n = 10), hu.Thor at 4 weeks post-transplantation (4w), hu.Thor (n = 9, 16-weeks) and hu.PBMC mice and analyzed with FCM for CD4 + and CD8 + T cell populations. a and c. Total numbers of CD4 + T cells (a) and CD8 + T cells (c). b and d. Percentage of CD4 + T cells (b) and CD8 + T cells (d). Data are presented as bar graphs with mean values +/− SEM using a two-tailed Mann-Whitney test, where p < 0.05 is considered as significance.

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