Extended Data Fig. 5: Performance comparison of MSL2 RT&Tag to RIP–seq.
From: Profiling RNA at chromatin targets in situ by antibody-targeted tagmentation
a) Volcano plot showing transcripts differentially enriched for MLE RIP–seq over input (fold change >2, FDR < 0.05, n = 3, GSE143455). Transcripts enriched for MLE are highlighted in red, nonenriched are in black, and depleted are in blue. b) Table comparing MSL2 RT&Tag and MLE RIP–seq in terms of number of cells, number of reads, and roX2 fold change enrichment for MSL2/MLE over control. c) Venn diagram showing the overlap between transcripts enriched for MSL2 RT&Tag and MLE RIP–seq with roX1 and roX2 being enriched in both. D) Pie charts showing the chromosomal distribution of transcripts uniquely enriched for MSL2 RT&Tag (left) and MLE RIP–seq (right).
