A naturally short-lived fish opens the gates for rapid exploration of vertebrate aging.
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References
Astre, G., Moses, E. & Harel, I. in Laboratory Fish in Biomedical Research (eds D’Angelo, L. & de Girolamo, P.) 245–287 (Elsevier, 2022).
Cellerino, A., Valenzano, D. R. & Reichard, M. Biol. Rev. Camb. Philos. Soc. 91, 511–533 (2016).
Harel, I. & Brunet, A. Cold Spring Harb. Symp. Quant. Biol. 80, 275–279 (2015).
Podrabsky, J. E. & Hand, S. C. J. Exp. Biol. 218, 1897–1906 (2015).
Valenzano, D. R. et al. Curr. Biol. 16, 296–300 (2006).
Astre, G. et al. Preprint at bioRxiv https://doi.org/10.1101/2022.01.10.475524 (2022).
Harel, I. et al. Cell 160, 1013–1026 (2015).
Harel, I., Valenzano, D. R. & Brunet, A. Nat. Protoc. 11, 2010–2028 (2016).
Reichwald, K. et al. Cell 163, 1527–1538 (2015).
Valenzano, D. R. et al. Cell 163, 1539–1554 (2015).
Dolfi, L., Ripa, R., Antebi, A., Valenzano, D. R. & Cellerino, A. Evodevo 10, 29 (2019).
Hu, C. K. et al. Science https://doi.org/10.1126/science.aaw2601 (2020).
Wang, W. et al. Changes in regeneration-responsive enhancers shape regenerative capacities in vertebrates. Science 369, eaaz3090 (2020).
Kelmer Sacramento, E. et al. Mol. Syst. Biol. 16, e9596 (2020).
Harel, I. et al. Identification of protein aggregates in the aging vertebrate brain with prion-like and phase separation properties. Preprint at bioRxiv https://doi.org/10.1101/2022.02.26.482115 (2022).
Cui, R. et al. Cell 178, 385–399.e20 (2019).
Nelson, J. S., Grande, T. & Wilson, M. V. H. Fishes of the World https://onlinelibrary.wiley.com/doi/book/10.1002/9781119174844 (2016).
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Harel, I. The turquoise killifish. Nat Methods 19, 1150–1151 (2022). https://doi.org/10.1038/s41592-022-01631-y
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DOI: https://doi.org/10.1038/s41592-022-01631-y
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