Extended Data Fig. 5: pH dependence of cAMPFIRE responses. | Nature Methods

Extended Data Fig. 5: pH dependence of cAMPFIRE responses.

From: Sensitive genetically encoded sensors for population and subcellular imaging of cAMP in vivo

Extended Data Fig. 5

Sensor signal (fluorescence ratio) in the absence (black; Apo) or presence (red) of 100 µM cAMP normalized to the dynamic range of the sensor at pH 7.3 under the same measurement conditions. Averaged data are presented as mean ± s.e.m. n = 3 measurements, each from a different protein aliquot, for each condition.

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