Extended Data Fig. 6: Additional example of VSV-G VLP Binding Event.
From: Capturing the start point of the virus–cell interaction with high-speed 3D single-virus tracking
a, 3D-TrIm render of BJ Fibroblast cells stained with SiR-650 (f-Actin). b, Distance-diffusivity trace of viral trajectory. This trajectory begins with rapid extracellular diffusion before binding to the surface. A small ~1 second detachment occurs before re-binding for several seconds and detaching again where skimming is observed with inhibited diffusivity compared to the initial free diffusion, followed by free diffusion that has greater diffusivity than observed while skimming, but lower than the initial free diffusion.
