Extended Data Fig. 7: Number of predicted protein complexes across cell types. | Nature Methods

Extended Data Fig. 7: Number of predicted protein complexes across cell types.

From: Quantification of extracellular proteins, protein complexes and mRNAs in single cells by proximity sequencing

Extended Data Fig. 7

(a) t-SNE plot of PBMC clusters, obtained using mRNA expression level. (b) Violin plots showing the number of predicted protein complexes per single cell, for each of the 8 clusters identified using mRNA data. The horizontal red lines indicate the total number of predicted protein complexes per cluster. In total, 61 protein complexes were detected across all 8 clusters, of which 37 complexes are unique. (c) Plot showing the number of protein complexes predicted by the algorithm at different number of cells. Here, various numbers of cells were randomly subsampled from each of the 8 clusters identified in (a), and the complex prediction algorithm was applied on the subsampled cells.

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