Extended Data Fig. 7: Complement control peak prioritization.
From: Multiplexed transcriptome discovery of RNA-binding protein binding sites by antibody-barcode eCLIP
A) Sorted bar plots ranked by two-sided enrichment peak p-values. Colors correspond to peaks annotated as matching known RBP function. Triplicate ABC and duplicate eCLIP datasets are displayed adjacent to each other. B) Schematic of SMI overlap with ABC peaks. C) Scatter plot of the percent of peaks removed by SMI compared to RNA-seq and CC normalizations for each barcode within the multiplex (rep 2 and 3). D) Cumulative count of histone genes across the top 100 ranked genes based on two-sided enrichment p-values using different methods of normalization. E) Sorted bar plots of ranked peaks by one-sided enrichment p-value < 0.001. Colors denote that the peak is within an annotated histone RNA.
