Extended Data Fig. 7: Performance of matching and integration on CODEX and CITE-seq murine spleen cells. | Nature Methods

Extended Data Fig. 7: Performance of matching and integration on CODEX and CITE-seq murine spleen cells.

From: Robust single-cell matching and multimodal analysis using shared and distinct features

Extended Data Fig. 7

(A) Performance of matching and integration during the sequential dropping of shared protein features. (B) Testing algorithm stringency between different methods. Increasing amounts of random spike-in noise was added to the data, and the matching accuracy and proportion of cells matched to X were quantified. (C) Testing algorithm stringency among different methods. Single-cell types in Y were completely removed before matching to X. The proportion of cells belonging to the deleted cell type in matched X cells was used to calculate the erroneous avoidance score. (D) t-SNE plots visualizing pre-integration and post-integration results with different methods.

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