Extended Data Fig. 6: Single-cell analysis of control and SHH-induced organoids.
From: Spatiotemporal, optogenetic control of gene expression in organoids
a. UMAP representation of all sequenced cells with > 800 UMIs and < 5% mtRNA, before filtering out two low-quality clusters (5 and 7). Left: samples of origin (controls in grey, induced in blue); right: identified clusters. b. Distribution of transcripts and gene counts and mtRNA % by clusters and samples. c. Cell number by cell type and sample. d. Heatmap of top 20 marker genes expression for all clusters.
