Extended Data Fig. 5: Reconstructions of OPUS-DSD and cryoDRGN on synthetic dataset of NEXT complex with a signal-to-noise ratio of 0.05.
From: OPUS-DSD: deep structural disentanglement for cryo-EM single-particle analysis
a). 3D density maps reconstructed by the decoder of OPUS-DSD using cluster centers shown in Fig. 6b. b). 3D density maps reconstructed by the decoder of cryoDRGN using cluster centers shown in Fig. 6b. c). 3D density maps reconstructed by cryoSPARC with particles in each class from OPUS-DSD. d). 3D density maps reconstructed by cryoSPARC with particles in each class from cryoDRGN.
