Extended Data Fig. 6: Distinguishing phenotypes of different severity during zebrafish development.
From: Uncovering developmental time and tempo using deep learning
(a-f) Detection of -BMP phenotypes of different strength. (a-e) Upper panels show the mean similarities and standard deviation of similarities of bmp (swr-/-) mutants (a) and -BMP drug-treated embryos with C5 (b), C4 (c), C3 (d) and C2 (e) phenotypes. The respective lower panels show significance levels of the difference from untreated embryos along the time axis in p-values determined using a nonparametric one-sided Mann-Whitney U test over each time point of the image series. No adjustments for multiple comparisons were made. n = 44 for all cases. (f) Dependency of the accuracy of abnormality detection on the number of embryos used for the analysis. Mean and standard deviation are shown for five repetitions with randomly selected samples. Raw data for analysis from https://doi.org/10.48606/15.
