Extended Data Fig. 3: Confirmation of DNA 6 mA methylation at RA6mATTY motif sites using PacBio sequencing of two A. muciniphila strains. | Nature Methods

Extended Data Fig. 3: Confirmation of DNA 6 mA methylation at RA6mATTY motif sites using PacBio sequencing of two A. muciniphila strains.

From: mEnrich-seq: methylation-guided enrichment sequencing of bacterial taxa of interest from microbiome

Extended Data Fig. 3

a, RA6mATTY (mediated by MTase AmuORF1905P) is one of the five methylated motifs detected in A. muciniphila (ATCC BAA-835) by PacBio sequencing as summarized in REBASE. b, DNA 6 mA methylation at RAATTY motif sites (light blue) is confirmed based on the high IPD ratios observed in PacBio sequencing data of the A. muciniphila strain isolated from the infant fecal sample GUT-3. c, DNA 6mA methylation at RAATTY motif sites (purple) is confirmed based on the high IPD ratio observed in PacBio SMRT sequencing data of another A. muciniphila strain.

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