Extended Data Fig. 3: The impact of lineage invasions on Np estimation.
From: A statistical method for quantifying progenitor cells reveals incipient cell fate commitments
a. Schematic plot of impact of lineage invasion. b. In each panel, the performance of Np estimation is assessed for a specific proportion of lineage invasions, ranging from 0.1% to 90%. The x-axis represents the average Np obtained from 1,000 repeats, while the y-axis denotes the actual number of progenitors. The horizontal error bars indicate the interquartile range of Np estimates and the trendline fitted with a linear model (LM) is shown in blue. The Pearson′s correlation coefficients and the corresponding P-values obtained from two-sided t-tests are shown on the top-left corner of each panel.
