Extended Data Fig. 4: Collaborative reconstruction of a branch structure by two annotators.

Black lines denote reconstructed edges, while red lines denote new edges to add to the reconstruction result. Annotators prepare the new edges based on their observation of imaging data (thick gray arrows), which typically takes several seconds per step. Thin black arrows show communication between the clients and the server, with a typical round-trip time of less than 100ms. Note that the reconstruction result at the client side may be incomplete. When incompleteness leads to incorrect operations, the reconstruction result is automatically updated. In this example, client B initially only has the reconstruction result of the right-side branch. After rejection by the server, the result for the left-side branch contributed by client A is automatically loaded, such that client B can connect to the correct node at the branch point.