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Constructing and personalizing population pangenome graphs

Nature Methods volume 21, pages 1980–1981 (2024)Cite this article

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Pangenome graphs signify a new frontier in genome representation. Recent advances in constructing and personalizing them mark progress in this area.

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Fig. 1: Workflow for the construction and personalization of pangenome graphs.

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Acknowledgements

R.C. was supported by Agence Nationale de la Recherche (ANR) grants ANR-22-CE45-0007, ANR-19-CE45-0008, PIA/ANR16-CONV-0005, ANR-19-P3IA-0001 and ANR-21-CE46-0012-03 and Horizon Europe grants 872539, 956229, 101047160 and 101088572. P.M. was supported by US National Science Foundation grant DBI2138585 and National Institute of General Medical Sciences award R01GM146462.

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Authors and Affiliations

  1. Institut Pasteur, Université Paris Cité, Sequence Bioinformatics Unit, Paris, France

    Rayan Chikhi & Yoann Dufresne

  2. The Pennsylvania State University, State College, PA, USA

    Paul Medvedev

Authors
  1. Rayan Chikhi
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  2. Yoann Dufresne
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  3. Paul Medvedev
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Correspondence to Rayan Chikhi.

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The authors declare no competing interests.

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Chikhi, R., Dufresne, Y. & Medvedev, P. Constructing and personalizing population pangenome graphs. Nat Methods 21, 1980–1981 (2024). https://doi.org/10.1038/s41592-024-02402-7

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