Extended Data Fig. 10: Correlation analysis between axis-on-a-chip propagation analysis and clinical data of donors. | Nature Methods

Extended Data Fig. 10: Correlation analysis between axis-on-a-chip propagation analysis and clinical data of donors.

From: Differentiating visceral sensory ganglion organoids from induced pluripotent stem cells

Extended Data Fig. 10

(a-e) Correlation analysis between donor’s clinical data and quantified amyloid or tau propagation amount at axis-on-a-chip. Donor data: a, MMSE-Z score; b, Semantic memory Z-score; c, Global amyloid PET SUVR; d, Brain MRI hippocampal adjusted volume (HVA); e, FDG PET SUVR at PCC (n=16). Each n are biological replicates. Used iPSC lines: 1-control, 4-sAD lines. (a-e) Kendall’s tau correlation analysis. ***P<0.001.

Back to article page