Fig. 5: Neuron subtyping based on spatial-connectivity patterns.
From: Connectivity of single neurons classifies cell subtypes in mouse brains
Top rows: biclustered spatially tuned connectivity similarity matrices, where different colors along the x and y axes indicate the clusters, and the index numbers of neurons in a specific s-type are shown on both x and y axes. Middle rows: triview visualization of neurons in CCFv3; neurons are rendered in the same colors as in the respective top-row clusters. A, anterior; P, posterior; D, dorsal; V, ventral; L, left; R, right. Bottom rows: dataset composition in each cluster. The percentage and neuron count of each dataset are labeled. D1, D2 and D3 refer to AIBS/SEU-ALLEN, MouseLight and ION, respectively. a–c, Subtyping of PL neurons for layer 2/3 (PL2/3) (n = 188) (a), layer 5 (PL5) (n = 795) (b) and layer 6a (PL6a) (n = 99) (c). d–f, Subtyping of MOs neurons in MOs layer 2/3 (MOs2/3) (n = 218) (d), layer 5 (MOs5) (n = 359) (e) and layer 6a (MOs6a) (n = 116) (f). g–i, Subtyping of thalamic neurons in VPL (n = 91) (g), VPM (n = 406) (h) and LGd (n = 78) (i).
