Extended Data Fig. 6: Distribution of DNA damage signals on coding genes, LINE1 and ERV elements.
From: Single-cell parallel analysis of DNA damage and transcriptome reveals selective genome vulnerability
a, Line plots showing the DNA damage levels around genic regions of genes with different expression levels in each brain cell type, respectively. b, Violin plots showing the average detected signal levels in compartments A and B (RPKM, in 250-kb non-overlapping bins) for non-targeting tagmentation control and ATAC-seq of mouse brain; for all box plots, hinges were drawn from the 25th to 75th percentiles, with the middle line denoting the median, whiskers denoting a maximum 2× the interquartile range and outliers indicated with dots; n = 4,089 (compartment A), n = 5,095 (compartment B) elements. c, Line plots showing the DNA damage levels around long interspersed nuclear elements-1 (LINE1) and endogenous retroviruses (ERV) elements in compartment A and compartment B, respectively, for different brain cell types.
