Extended Data Fig. 3: Accumulation of DNA damage induced by oxidative stress.
From: Single-cell parallel analysis of DNA damage and transcriptome reveals selective genome vulnerability
a, Relative enrichment of DNA damage peaks in control and 48-hr post H2O2 treatment HeLa cells in different short tandem repeat (STR) subfamilies. b, Barplots showing the relative enrichment of conserved and induced DNA damage peaks in different genomic regions. c, Line plots showing the DNA damage levels (RPKM) on conserved and induced peaks in HeLa cells of different treatments. d, Line plots showing the DNA damage levels (RPKM) on simple repeats, Z-form DNA and putative G-quadruplex sequences in control and 48-hr post H2O2 treatment HeLa cells. e, Line plots showing DNA damage signals, ATAC-seq signals and RNA-seq signals around endogenous retroviruses (ERV) long terminal repeats (LTR) regions in compartment A and compartment B of control and 48-hr post H2O2 treatment HeLa cells.
