Extended Data Fig. 7: Tumor-agnostic copy-number based tumor fraction estimation in stage III and IV melanoma and cancer-free control samples.

Samples include cancer-free controls (n = 10); stage III melanoma (pre-surgery; n = 10) and stage IV melanoma (pre-treatment; n = 4). Dotted line at 0.03 represents the limit of detection of ichorCNA. For boxplots, the lower and upper ends of boxes represent the 25th and 75th percentiles of the data, respectively, and the horizontal lines represent the median.