Fig. 3: InterpolAI interpolation for stacks of MRI and light-sheet microscopy images. | Nature Methods

Fig. 3: InterpolAI interpolation for stacks of MRI and light-sheet microscopy images.

From: InterpolAI: deep learning-based optical flow interpolation and restoration of biomedical images for improved 3D tissue mapping

Fig. 3

a, Tissue-cleared light-sheet images were interpolated skipping seven slides between adjacent sections, thereby generating seven slides. b, Qualitative comparison of linear, XVFI and InterpolAI interpolations to the authentic image for the middle-interpolated light-sheet image (image 4). Arrowhead shows linear interpolation creates double boundary lines around bronchioles. In the second row, the arrowhead shows photobleaching in authentic reduced by linear interpolation and completely removed by InterpolAI (arrow). Dashed arrow shows XVFI reduced photobleaching but did not remove it. Second dashed arrow shows XVFI elongated the right edge of a bronchiole. c, PCA of 13 Haralick features for authentic, linear, XVFI and InterpolAI-interpolated light-sheet images for various numbers of skipped light-sheet images. Mean Euclidean distance of interpolated images from authentic images based on 13 Haralick features. d, Euclidean distance by slide of interpolated images from authentic images based on 13 Haralick features for various numbers of skipped light-sheet images.

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