Extended Data Fig. 4: Generation of CIGS.
From: High-throughput profiling of chemical-induced gene expression across 93,644 perturbations
a and b, TSNE plot of all compounds in MDA-MB-231 cells (a) and HEK293T (b). JQ1 treatment serves as a positive control in both HiMAP-seq and HTS2 experiments. Each dot represents a compound. c, Comparison of HiMAP-seq with HTS2. Heat maps displaying the log2(fold change) of genes in MDA-MB-231 cells treated with 10 μM JQ1. The log2(fold change) were detected using HiMAP-seq or HTS2. d, Schematic diagram illustrating the data composition of CIGS.
