Fig. 1: Spacedust algorithm.
From: De novo discovery of conserved gene clusters in microbial genomes with Spacedust
a, Workflow. b, Starting from single-gene clusters, clusters are iteratively merged if this increases their conservation score until all scores are maximal. Colored boxes indicate pairs of homologous proteins found by Foldseek. Cluster conservation is measured by combining a clustering P value and an ordering P value.
