Extended Data Fig. 5: Titration of KCl into the paused transcriptional elongation complex system (D4).
From: Foundation model for efficient biological discovery in single-molecule time traces
a,b, 2D UMAP projections of embeddings from uncurated traces under different KCl concentrations in Atlas coordinates (a) and system-specific coordinates (b). c, TODPs of traces from the different KCl concentration conditions. d, FRET histogram of traces from the different KCl concentrations. e,f, 2D UMAP projections of the 10% of embeddings with lowest LSE from traces under the different KCl concentrations in Atlas coordinates (e) and system-specific coordinates (f). g, TODPs of 10% lowest LSE traces from the different KCl concentration conditions. h, FRET histograms of the 10% of traces with lowest LSE from the different KCl concentrations. i, FRET histograms of manually curated traces from the different KCl concentrations.
