Supplementary Figure 11: Injection/removal of neurons with NMS.

(a) The heat map shows the cross-temporal decoding performance after neurons with NMS were added to the FEF population. (b, c) The results of the state space analysis are plotted as in the previous figure. (d) The average shift in the cluster centers between the Delay 1 and Delay 2 responses are shown in the Delay 1 (significant, p < 0.001, g = 9.53) and Delay 2 space (significant, p < 0.001, g = 10.16). (e) The heat map shows the cross-temporal decoding performance after the population of neurons with NMS in the LPFC were matched to those in the FEF in terms of effect sizes and numbers. (f, g) The results of the state space analysis are plotted as in the previous figure. (h) The average shift in the cluster centers between the Delay 1 and Delay 2 responses are shown in the Delay 1 (non-significant, p ~ 0.24 and Delay 2 space (non-significant, p ~ 0.13. By making the neurons with NMS in the LPFC more like those in the FEF, the code morphing in the LPFC was no longer significantly different from chance. n.s. - not significant. ** - indicates that the 2.5^th and 97.5^th percentile ranges did not overlap with the chance level. Horizontal dashed lines represent the 97.5^th percentile of the shifts obtained by chance. The horizontal red line in box plots represents the median of the distribution.