Supplementary Figure 2: Dependence of sheath elongation on [Ca2+]i properties
From: Regulation of developing myelin sheath elongation by oligodendrocyte calcium transients in vivo
(a-c) Change of sheath length (in 68 sheaths from 6 animals) correlates significantly with sheath [Ca2+]i transient (a) duration, (b) amplitude and (c) area (ʃ[ΔF/F] dt). (d) Change of sheath length does not correlate significantly with soma [Ca2+]i transient rate (in 54 sheath-soma pairs from 6 animals). (e) Increase of sheath length and [Ca2+]i transient rate in 14 lengthening sheaths which were of constant length for at least 1 hour before lengthening started, with data aligned at t=0 at the start of growth. [Ca2+]i transients precede sheath growth by ~1 hour. Data are mean±SEM.
