Supplementary Figure 8.: Photoinhibition of the CaMKIIα+ MPA–vPAG circuit abolishes object exploration.
From: Medial preoptic circuit induces hunting-like actions to target objects and prey

a. Left, CaMKIIα::eNpHR3.0MPA-vPAG mice (n = 8) move presented objects less than control CaMKIIα::eYFPMPA-vPAG mice (n = 5, Two Way RM ANOVA, 5 min, P < 0.01; 10 min P = 0.135; 15 min, P = 0.643; 20 min, P = 0.562). Line graph indicates mean (lines) ± SEM (error bars). Right, Curves for individual mice. b. Total food intake. CaMKIIα::eYFPMPA-vPAG (n = 5) and CaMKIIα::eNpHR3.0MPA-vPAG (n = 6) mice (Unpaired t-test, P = 0.936) eat similar amounts. Bar graphs represent mean (bars) ± SEM (error bars) and individual data (colored-lines). See the detailed statistical values in Supplementary table 1. * P < 0.05, n.s. not significant